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Making things, learning and having fun · 960 ideas

Comb DNA databases with 950 agents and spot a new enzyme system

Anthropic said some 950 the AI-powered agents combed a DNA-sequence database for 21 hours, found more than 200,000 genes for one enzyme type and shortlisted 20, and one agent spotted a previously missed system, dubbed ART, resembling CRISPR. Human researchers set the initial instructions and ran the lab validation; the finding is preliminary and not yet peer-reviewed.

The AI helped write the scripts that tested a puzzle image for hidden data

A puzzle solver designed tests for whether a circulated image hid steganographic data, and used AI to help write the scripts and qualify signal and noise across JPG compression formats. He ran the tests with standard tools on every copy of the image he could find, and nothing extracted from any of them, which settled that the image itself carries no hidden payload.

Design quantum circuits that beat the best published ones

Unite.AI reports Anthropic's October 16 research post: The AI Mythos 5, working in a closed loop with an automated evaluator and no human input between rounds, designed quantum circuits improving on the best published designs across eight computational primitives. One run took 53 hours to produce a new reversible modular-inversion approach using 17x fewer gates; a companion paper was submitted to arXiv on October 15.

Four months of spare time with AI, and the hiking game I always wanted is live

He spent about four months of spare time building Switchback, a cozy hiking simulator like old park management games, with AI writing the code and judging the look of the assets. It ingests real map heights to build its trails, and has its own water, wind and day and night systems. He launched it on iPhone and iPad yesterday and people are playing it.

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Every idea is a real post from someone who tried it, summarized in our words, with a link to the original. App names are swapped for plain words.