His Microbiome Repo catalogs every public human gut metagenome, more than 500,000 samples, with metadata pulled straight from sequence archives, papers and supplements. It was built with about $5,000 in an AI app API credits from the Anthropic AI for Science program, with AI taking on the metadata curation he calls the most tedious but critical part of microbiome research.
Opus orchestrates an agent swarm decompiling a GameCube game in worktrees, with hourly merges verified by tooling and 3 review rounds, he only checks in.
This only partly worked. Worth knowing before you try it.
Travel advisor Marissa Waiters reports the AI scanned her email inbox and located 18 free night vouchers, then organized and filed them for easy access — travel value that was effectively lost in the inbox.
A maker had the AI redesign his KiCad board, including selecting parts from JLCPCB's catalog and suggesting cheaper equivalent components that cut his bill of materials significantly. When assembly proved too expensive, the AI redrew the schematic around through-hole parts he could source himself.
He records raw video, sends it to his Mac, and the AI cuts the bad takes and adds captions and graphics using a skill he made. He says he does not open a video editor anymore.
Before a Wednesday conference trip to Japan, the AI proactively reviewed the author's Google Schedule, noticed the Visit Japan registration was missing, and messaged him. After he logged in, it auto-populated his flight and hotel details so he could finish with one final click.
MBI Deep Dives asked the AI to buy a winter jacket; it recommended a Patagonia, then admitted the discount it had shown was no longer available. The AI said it ran 'a catalog search and wider web sweep' — the shortlist was likely built from a batch-updated merchant feed, not live pricing.
This one went wrong. See what happened before you try it.
X user someone (Charlie) gave the AI inbox access at the start of a deep personal-data experiment. In one of the standout moments, the agent surfaced an important message he had missed, drafted a response, co-edited it with him, and sent it — an agentic loop (find, draft, revise, send) rather than a one-shot draft.
Coach Casey Kenny asked his AI 'Milo' to book a flight for an October 21 keynote in Dallas; Milo returned United options and Kenny selected option 3. The video shows the actual booking interaction for a business trip.
Thanks to the AI he has been working on a 4 player version of Wizard of Wor for the Atari 800 that uses all 4 joystick ports, so far in an emulator, with a real Atari test to come. He says he can now play his favorite games with fun options that never existed before.